We aspire to make innovative discoveries with high impact on biology and medicine!
Although sleep exists in virtually all animals and is essential for normal brain functions, the molecular underpinnings of sleep regulation is currently unknown. Additionaly, almost nothing is known about human emotions at the molecular level. Fear is a basic emotion that enhances animal survival by triggering the fight, flight, or freezing response to danger. We hope to discover the molecular circuits of sleep and fear by combining mouse forward genetic screening, classical biochemistry, cutting-edge mass spectrometry and neuroscience approaches. We believe that these fundamental discoveries will drive the development of novel medicines for sleep disorders and fear-related mental disorders.